KYGEVVI support and resources

ONWARD is a single point of entry for patients prescribed KYGEVVI

Once enrolled, prescribed patients and their caregivers will receive:

Personalized support from a dedicated Care Coordinator* throughout the treatment journey
Coordination between PANTHERx Rare, the exclusive specialty pharmacy for KYGEVVI, and the ONWARD Mito Case Manager (MCM) throughout the insurance approval process
Help with reviewing insurance coverage and potential financial assistance options
Preparation and administration support from PANTHERx Rare^†
Tools and resources to get started with, and ongoing support for, their prescribed treatment

*ONWARD Care Coordinators do not provide medical advice and will refer patients to their healthcare professional for any questions related to their treatment plan.

^†PANTHERx Rare will offer preparation and administration support for all patients.

There are 3 ways to get started with ONWARD.

Ask your doctor to sign you up

Visit ucbONWARD.com/KYGEVVI to download an ONWARD start form and take it to your doctor

Call 1-844-ONWARD-1 (1-844-669-2731) Monday-Friday, 8:00 AM-8:00 PM ET

Helpful resources

Download these resources to find more information about KYGEVVI.

KYGEVVI Patient Education Brochure

Patient Brochure

ONWARD Brochure

ONWARD Brochure

The TK2d community is small but mighty

Despite being small, the TK2d community has strong partnerships with organizations like United Mitochondrial Disease Foundation (UMDF) for patient advocacy, International Mito Patients (IMP) for global connections, MitoAction for support, and Muscular Dystrophy Association (MDA) for reaching the neuromuscular disease community. Discover more about each of these groups now:

Frequently asked questions (FAQs)

Find answers to common questions about TK2d and KYGEVVI.  If you have any medical questions, please ask your doctor.

INDICATION

KYGEVVI is a prescription medicine used for the treatment of thymidine kinase 2 deficiency (TK2d) in adults and children with a symptom onset on or before 12 years of age.

IMPORTANT SAFETY INFORMATION

KYGEVVI may cause serious side effects including elevated liver enzyme levels. Increased liver enzyme levels in your blood are common with KYGEVVI. Your healthcare provider will do blood tests to check your liver enzyme levels before starting treatment and during treatment with KYGEVVI.

Tell your healthcare provider right away if you develop any signs or symptoms of liver problems, including loss of appetite, pain on the right side of your stomach area, dark or amber-colored urine, yellowing of your skin or the white part of your eyes, nausea and vomiting, or itching.

KYGEVVI may cause stomach and intestinal (gastrointestinal) problems. Diarrhea and vomiting are common with KYGEVVI, but may also be severe and lead to hospitalization. Tell your healthcare provider right away if you have diarrhea or vomiting during treatment with KYGEVVI that lasts longer than a few days.

The most common side effects of KYGEVVI include diarrhea, stomach area (abdominal) pain including pain in the upper stomach area, vomiting, and increased liver enzyme levels in your blood.

Your healthcare provider may change your dose, temporarily stop, or permanently stop treatment with KYGEVVI if you develop certain side effects.

Before taking or giving KYGEVVI, tell your healthcare provider about all of your medical conditions, including if you have or have had liver problems. In addition, tell your healthcare provider if you are pregnant or plan to become pregnant. It is not known if KYGEVVI will harm your unborn baby. Also, tell your healthcare provider if you are breastfeeding or plan to breastfeed. It is not known if KYGEVVI passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby if you take KYGEVVI. Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

These are not all of the possible side effects of KYGEVVI. Call your doctor for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088. You may also report side effects to UCB, Inc. at UCBCares® (1-844-599-CARE [2273]).

Please see additional information in the Patient Information Leaflet.